Scrambler Therapy is a proven, unique, non-invasive method for rapid treatment of chronic intractable neuropathic and cancer related pain.
Scrambler Therapy is a new electroanalgesia methodology specifically studied for neuropathic pain, oncologic pain, and in general for pain non-responsive to other types of drugs and forms of electrical stimulation therapies (TENS, spinal cord stimulator)
Five independent channels are available to transmit the artificial “no pain” messages via surface electrodes (non-invasive) placed on the skin outside the region of the patient’s pain. Protocols are different based on the types of pain treated. It stimulates C fibers (pain carrying fibers) in a physiological form vs. TENS unit excessively stimulates A-Beta fibers to suppress signal transmission by C-fibers.
It was invented by Prof. Giuseppe Marineo around 2003 at the University of Rome, Italy. It received FDA clearance in 2009.
What is the efficacy of Scrambler Therapy?
In general, it is operator and patient (type of condition) dependent. In clinical trials of CINP (Chemotherapy Induced Peripheral Neuropathy), efficacy has been around 60%, however they can be higher than 80%.
Which are the effects of combinations with other analgesic therapies?
Scrambler Therapy is a stand-alone medical electroanalgesia device and does not require combinations with other analgesic therapies. The usage of anticonvulsants for analgesic purposes generally calls for a higher number of treatments. It is also possible to continue the anticonvulsants analgesic therapy, however in this case, results are not as good and relapse is quicker. From studyphase data the combination with Ketamine is incompatible since it seems to block the analgesic efficacy of the treatment.
Painful Peripheral Neuropathy
Complex Regional Pain Syndrome (CRPS / RSD)
Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Intractable Cancer Pain
Failed Back Surgery Syndrome
Sciatic and Lumbar Pain
Post-Herpetic Neuralgia (PHN)
Brachial Plexus Pain
Chronic Neuropathic Pain, Allodynia, Hyperalgesia
The patient visits the practice for 10 treatment sessions on average. One session per day over a period of two weeks (weekdays). Treatment sessions may last from 30 to 45 minutes. Booster cycles are given when needed for symptoms recurrence.
During the first session, after the correct electrode positioning and fine-tuned stimulation levels, the patient may notice significant improvements in a short period of time. In the subsequent sessions, the patient may realize that pain relief is prolonged (reduced intensity and duration). So far Scrambler Therapy does not have any known side effects except mild irritation at the site of electrode placement
Scrambler Therapy® Technology MC-5A is a U.S. FDA 510(k)-cleared (# K142666) and European CE mark-certified (#CE 0470) pain therapy medical device.
The Scrambler Therapy device has been in active use at MD Anderson Cancer Center, Mayo clinic, John Hopkins, MUSC (Medical University of South Carolina), and Walter Reed Army hospital.
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